pulmonary surfactant in premature babies

UpToDate electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine Allergy and Immunology Cardiovascular Medicine Emergency Medicine Endocrinology and Diabetes Family Medicine Gastroenterology and Hepatology Hematology Infectious Diseases Nephrology and. This process is slower in newborns especially those born prematurely than in adults or those with lung injury.


Introduction Respiratory Distress Syndrome Of The Newborns Rds Respiratory Distress Syndrome Respiratory Distress Syndrome Newborn Bronchopulmonary Dysplasia

Babies born this early have a hard time breathing.

. The branches of the babys lungs are forming as well as the cells that make surfactant a natural substance that lines the tiny air sacs called alveoli in the lungs to make breathing possible. While a small amount of surfactant is now present the lungs are still immature. It is then recycled in a highly complex and regulated mechanism.

Surfactant replacement therapy is a crucial part of management of RDS and newer protocols for its use recommend early administration and avoidance of mechanical ventilation. Methods of maintaining babies on non-invasive respiratory support have been further developed and may cause less distress and reduce chronic lung disease. Pulmonary surfactant is synthesized assembled transported and secreted into the alveolus where it is degraded.

Overview of Surfactant Metabolism.


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